- From this game forward, Dr. Cortex was given a much deeper voice, courtesy of voice actor Clancy Brown, and Lex Lang later on.

- The 3D model used for Crash's character in this game was recycled for a number of sequels and spin-offs: Crash 3, CTR, XS, N-Tranced and Fusion. Thus, it's Crash's most widely recognized appearance.

- This famous Crash model is composed of 532 triangles. In this particular game, it has over 9000 frames of animation.

- Crash's burning animation is that of Crash 1, and it's fairly noticeable how it makes Crash change to his previous model (except when he's wearing the Jet-Pack). The same thing applies to Crash 3.

- At least one entire level in playable form was removed before the game was released. The level showed a snow theme, but very different in appearance from those seen in the game.

- Tiny's provisory name can still be seen in the US NTSC version of the game, if the player pauses it in his boss fight (it displays Taz Tiger, which was probably just a filler until a name was given to him, or just a mistake).

- This game is where Crash's pink boxers are first seen (when him and Polar run into an explosive Crate, or when Crash gets electrocuted).

- The level "Hang Eight" is named after the term "hang ten" used in surfing. Since bandicoots only have 8 toes, the level is named "Hang Eight" instead.

- The Japanese version of the game features Aku Aku giving out hints to the player. This makes this game his first speaking appearance, and not actually Crash 3.

- Coincidentally, there is an actual street in Louisiana called N. Gin Street.

- As found by Hacc, Monty Hall was the original name for the Warp Rooms. If one takes a look at the game's coding, each Warp Room is listed as "obj_monty_hall". The same happens in Crash 3, since it was built on a Crash 2 basis. This is a reference to the game show host Maurice "Monty Hall" Halperin.